Exploration of the anticandidosic activity of Piptadeniastrum africanum Hook (Fabaceae)
Keywords:
Antifungal activity, anticandidosic activity, Piptadeniastrum africanum, CandidaAbstract
Aim : Natural substances which derive from plants, have multiple interests, both in the cosmetic and pharmaceutical domain. In this context, we investigated the anticandidosic activities of Piptadeniastrum africanum , a medicinal plant used in the Haut-Sassandra Region to treat bacterial and fungal infections.
Methods : In order to be able to exploit a possible therapeutic activity, the aqueous and ethanolic extracts 70% of Piptadeniastrum africanum were tested on Candida albicans , Candida tropicalis and Candida Glabrata using the agar diffusion technique.
Results : The 70% ethanolic extract exhibited the best antifungal activity on Candida tropicalis and Candida albicans with respective CMFs of 12.5 mg /mL and 25 mg /mL.
Conclusions : The results obtained in this study, shows the richness of Piptadeniastrum africanum in chemical substances and which could represent a new potential source of bioactive molecules in therapeutics.
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