Phytochemical Screening and anti-microbial activity of Momordica charantia Linn

Authors

  • Amit Ingle Bajirao Karenjekar College of Pharmacy, Sakoli, Maharashtra
  • Ranjeeta Kapgatte Bajiraoji Karanjekar College of Pharmacy, Sakoli, Maharashtra

Keywords:

Momordica charantia, karalla, E.coli, Antimicrobial Activity

Abstract

Momordica charantia Linn. (Karela) commonly known as bitter melon or bitter guard is tropical and subtropical climber of family cucurbitaceae. Traditionally it possesses many uses as Antidiabetic, Carminative, Anthelmintic Antimalarial and Antimicrobial, Antiviral, Anti-carcinogenous, Contraceptives, Immmunostimulant, and Laxative, Antioxidant and Insecticidal. It indicates in skin treatment (eczema, acne, mycoses, scabies and hexoroid). In the present study we carried out phytochemical screening to identify phytoconstituents present in plant. Along with its antimicrobial activity against E. Coli by Cup plate method. Phytochemical screening reveals that presents of various phytoconstituents such as Alkaloids, Saponin, Cardiac Glycosides, Tannins, Protein and Flavonoids. Momordica charantia shows significant antimicrobial activity against E.Coli.

Downloads

Download data is not yet available.

References

Taylor L: Technical Data Report for Bitter melon (Momordica charantia) Herbal Secrets of the Rainforest. 2nd edition. Sage Press 2002. Austin.

Kirtikar KR and Basu BD: Indian medicinal plant. 1987; 1130.

Beloin N, Gbeassor M, Akpagana K, and Hudson J, de Soussa K, Koumaglo K and Arnason JT: Ethnomedicinal uses of Momordica charantia (Cucurbitaceae) in Togo and relation to its photochemistry and biological activity. J Ethnopharmacol 2005; 96: 49-55.

Grover JK and Yadav SP: Pharmacological actions and potential uses of Momordica charantia. A Rev J Ethnopharmacol 2004; 93(1): 123-132.

Ng TB, Chan WY and Yeung HW: Proteins with abortifacient, ribosome inactivating, immunomodulatory, antitumor and anti-AIDS activities from Cucurbitaceae plants. Gen Pharmacol 1992; 23: 579-590.

Scartezzini P and Speroni E: Review on some plants of Indian traditional medicine with antioxidant activity. JEthnopharmacol71: 2000; 23-43.

Zafar R and Neerja: Momordica charantia-a review. Hamdard Medicine 34: 1991; 49-61.

Duke JA: Handbook of medicinal herbs. CRC Press, Boca Raton FL 1985; 315-316.

Agrawal M and Kamal R: In vitro clonal propation of Momordica charantia L. Ind J Biotech (3): 2004; 426-430.

Kumar DS, Sharathnath KV, Yogeswaran P, HaraniA, Sudhakar K, Sudha P and Banji D: A medicinal potency of Momordica charantia. Int J Pharmaceu Sci Rev Res 1(2): 2010; 95.

Nadkarni KM: Indian Material Medica. Vol 1, Popular Prakashan 1993; 805-806.

Dhalla NS, Gupta KC, Sastry MS and Malhotra CL: Chemical composition of the fruit of Momordica charantia Linn. Ind J Pharmacol 2011; 23: 1961; 128.

Jagessar RC, Mohamed A and Gomes G: An evaluation of the antibacterial and antifungal activity of leaf extracts of Momordica charantia against Candida albicans, Staphylococcus aureus and Escherichia coli. Nat Sci 2008; 6(1).

Horax R, Hettiarachchy N and Islam S: Total Phenolic contents and phenolic acid constituents in four varieties of bitter melons (Momordica charantia) and antioxidant Activities of their extracts. J Food Sci 2005; 70.

Sathishsekar D and Subramanian S: Antioxidant properties Of Momordica Charantia (bitter gourd) seeds on Streptozotocin induced diabetic rats. Asian Pacific J Clint 2005; 14(2): 153-158.

Garau C, Cummings E, Phoenix DA and Singh J: Beneficial effect and mechanism of action of Momordica charantiain the treatment of diabetes mellitus a mini review. Int J Diab Metabol 2003; 11: 46-55.

Downloads

Published

2018-07-30

Issue

Section

Research Articles

How to Cite

1.
Ingle A, Kapgatte R. Phytochemical Screening and anti-microbial activity of Momordica charantia Linn. Int J of Pharmc Res [Internet]. 2018 Jul. 30 [cited 2024 Mar. 1];8(7):63-5. Available from: https://ssjournals.co.in/index.php/ijpr/article/view/4845

Similar Articles

1-10 of 164

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)

1 2 3 4 5 6 7 8 9 10 > >>