Evaluation of anti-epileptic activity of fresh fruit juice of Moringa oleifera against maximal electroshock (M.E.S) and Picrotoxin (PTX) induced convulsions in mice.

Authors

  • Quazi Emadoddin Sant Gandge Baba Amravati University,Amravati, Maharashtra INDIA

DOI:

https://doi.org/10.7439/ijpr.v6i8.3455

Abstract

Moringa oleifera (Moringaecea) are used in Indian traditional medicine and in folklore for many diseases and extensively used as CNS depressant traditionally. The interesting things of this plant are each part of Moringa oleifera is used as medicines. The present work has been carried out to evaluate the anti-epileptic activity of fresh fruit juice of Moringa oleifera against maximal electroshock (M.E.S) and Picrotoxin (PTX) induced convulsions in mice at different dose level (100ml/kg. p.o and 50ml/kg. p.o). Diazepam (5mg/kg. p.o) and Phenytoin (25mg/kg. i.p) were used as reference standard drugs. The data obtained indicates that the fresh fruit juice of Moringa oleifera at the dose of (50ml/kg p.o and 100ml/kg p.o) shows anticonvulsant activity against Maximal electroshock and Picrotoxin induced convulsion in mice.

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Author Biography

  • Quazi Emadoddin, Sant Gandge Baba Amravati University,Amravati, Maharashtra INDIA
    Master of Pharmacology

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Published

2016-08-30

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Section

Research Articles

How to Cite

1.
Emadoddin Q. Evaluation of anti-epileptic activity of fresh fruit juice of Moringa oleifera against maximal electroshock (M.E.S) and Picrotoxin (PTX) induced convulsions in mice. Int J of Pharmc Res [Internet]. 2016 Aug. 30 [cited 2025 Mar. 14];6(8):278-81. Available from: https://ssjournals.co.in/index.php/ijpr/article/view/3455