Prescription pattern of antimicrobials in tertiary care hospital in central India
DOI:
https://doi.org/10.7439/ijpr.v5i2.1759Keywords:
Japanese encephalitis, Clinical profile, SequelaeAbstract
Objective: Antimicrobial agents are the greatest contribution to 20th century, which are used for cure and prevention of infections. Widespread use of antimicrobials has facilitated the development of resistance. Aim : the study was to assess the use of antimicrobials in tertiary care hospital in Maharashtra. Method: Prescription audit was done to assess the use of antimicrobials. Total 1942 prescriptions were analyzed for average number of drugs prescribed, antimicrobials prescribed by generic name or brand name, percentage of antibiotics among the prescribed drugs, use of fixed drug combinations, if any. Statistical analysis used : Data was analyzed by percentage. Result: Demographic analysis showed that out of 1942 patients in OPD, most were male (56.38) and in the age group between 35 to 50 years. In 1942 prescription, 30.25% drugs were antimicrobials. Three drugs were prescribed in 52.15% of the prescription, followed by 4 drugs in 19.78% prescriptions. 79.18% prescriptions were prescribed by generic name while 20.82% were prescribed by brand name. 29.18% of drugs were fixed dose combinations of all the antibiotics were prescribed empirically on the basis of provisional diagnosis. Of the total of antibiotics prescribed, amoxicillin was prescribed in 50.66% of patients, followed by cotrimoxazole in 26.05 % patients, cephalexin (8.50%) were used commonly. Conclusion: The rational use of antimicrobial agents is one of the main contributors to control worldwide emergence of antibacterial resistance, side effects and reduced cost of the treatment.Downloads
References
KD TRIPATHI. Antimicrobial drugs, Essentials of Medical Pharmacology.7 th Edition,12. New Delhi JAYPEE Brothers medical publishers, 2013; 688-704
Woldu MA, Suleman S, Workneh N, Berhane H. Retrospective study of the pattern of antibiotic use in Hawassa University Referral Hospital Pediatric Ward, Southern Ethiopia ;J App Pharm Sci; 2013;3(02):93-8.
World Health Organization Financing of Health in India Available from: http://www.ino.searo.who.int/Linkfiles/ Other_Content_WHD11-Seinar _Presentation-WRpdf.
Amane H, Kop P. Prescription analysis to evaluate rational use of antimicrobials. Int J Phar. ma and Biosci 2011; 2(2); 314-319.
Ernest J.S. Resistance to antimicrobials in humans and animals. BMJ ;2005,331:1219-20.
Goossens H. Antibiotic consumption and link to resistance. Clin Microbiol Infect. 2009 Apr;15 Suppl 3:12-15.
MacDougall C, Polk RE. Antimicrobial stewardship programs in health care systems. Clin Microbiol Rev ;2005 Oct;18(4):638-56.
Sharma M, Eriksson B, Marrone G, Dhaneria S, Lundborg CS. Antibiotic prescribing in two private sector hospitals; one teaching and one non-teaching: a cross-sectional study in Ujjain, India. BMC Infect Dis. 2012;12:155.
Khan FA, Singh VK, Sharma S, Singh P. Prospective Study on the Antimicrobial Usage in the Medicine Department of a Tertiary Care Teaching Hospital. Journal of Clinical and Diagnostic Research;2013 Jul ;Vol-7(7):1343-46.
Das BP, Sethi A, Rauniar GP, Sharma SK. Antimicrobial utilization pattern in outpatient services of ENT department of tertiary care hospital of Eastern Nepal. Kathmandu Univ Med J. (KUMJ) 2005;3:370-75.
Sharma R, Khajuria B. Prescribing practices of doctors in rural and urban India. J Clin Diag Res 2009;3;1480?82.
Babalola CP, Awoleye SA, Akinyemi JO, Kotila O. Evaluation of prescription pattern in Osun State (Southwest) Nigeria. J Public Health Epidem 2011;3:94?8.
] Saurabh MK, Jaykaran,Yadav AK, Jyoti N. Study of prescribing pattern and assessment of rational use of drugs in tertiary hospital, Rajasthan. J Pharm Res 2010;3(3):474?7.
Patel V, Vaidya R, Naik D, Borker P. Irrational drug use in India: A prescription survey from Goa. J Postgrad Med. 2005;51:9?12.
Patil S, Kachare A, Shaikh T, Nikam SS. Evaluation and prescribing pattern study of antibacterial agents in Medicine out-patient department of a teaching and referral Hospital in satara district area. UJP 2014;03 (01):75-8.
Hanssens Y, Ismaeili BB. Antibiotic prescription pattern in a medical intensive care unit in Qatar. Saudi Med J 2005;26:1269-76.
Downloads
Published
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- Author must Submit Copyright form After acceptance of Article