Evaluation of intrathecal buprenorphine as an adjuvant to bupivacaine for lower abdominal surgeries
Keywords:
Buprenorphine, Bupivacaine, Intrathecal, Haemodynamic, Sensory, Motor blockAbstract
Aim and Objectives: To evaluate the effect of Inj. buprenorphine 60 mcg as an adjuvant to intrathecal bupivacaine 0.5% (heavy) 3 ml on quality of sensory and motor block and haemodynamic parameters.
Method: Total 40 patients were randomly allocated in two groups having 20 patients each. ‘Group B’ received 15 mg (3 ml) of 0.5% hyperbaric bupivacaine heavy with 60 µg of buprenorphine (0.2 ml) (Study group) and ‘Group N’ received 15 mg (3 ml) of 0.5% hyperbaric bupivacaine heavy with 0.2 ml Normal saline (control group).
Results: Buprenorphine group had a significant faster onset and prolongs the duration of sensory and motor blockade than control group. Decrease in MAP and PR was observed in both the groups after subarachnoid block but the vital parameters between the two groups were comparable during different time intervals. The quality of block was found to be better in study group but difference was not significant. 3 patients in group N and 1 patient in group B required sedation. Both groups had minimal side effects but postoperative nausea and vomiting was more in buprenorphine group.
Conclusion: The intrathecal buprenorphine (60µg) can be used as a better adjuvant to 0.5% (heavy) bupivacaine in spinal anesthesia for lower abdominal surgeries.
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