Thiazolidinediones as potent anticancer agents: A Review
Keywords:
Anticancer activity, cancer, PPAR-γ, ThiazolidinedioneAbstract
Heterocyclic compounds and their derivatives has been an interesting field in medicinal chemistry because of their biological and pharmacological properties. Heterocyclic compounds are cyclic compounds in which the ring contains carbon, one or more atoms of other elements, commonly called as hetero atoms. Heterocyclic compounds usually contain hetero atoms like nitrogen, sulphur and oxygen. This review reflects the contribution of Thiazolidinedione as a scaffold to develop novel class of anticancer agents through PPAR-γ activation mechanism.
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