Molecular Docking Study on CD14 Receptor of Human Macrophage Cells by Screening Active Compounds Present in Clerodendrum Inerme.

Authors

  • Rachinnth Ravichandran St. Joseph's College of Engineering
  • Akash Lashmanasamy St. Joseph's College of Engineering
  • Kalavathy Gengiah St. Joseph's College of Engineering
  • Sivaraj C ARMATS Bioteck Training and Research Institute
  • Arumugam P ARMATS Bioteck Training and Research Institute

Keywords:

admetSAR, CD14 Receptor, Clerodendrum inerme, Monocytes, Molecular Docking, iGEMDOCK, Immunosupression

Abstract

CD14 is a key cell surface receptor present on macrophage cells which play a major role in immune functions. CD14 along with TLR 4 activate NF-?B inflammatory pathway, plays a role in innate immunity and host defence, and induce proinflammatory cytokines and much more. CD14 receptor on monocytes have been linked to the activation of monocytes and its implication in the conversion of monocytes into macrophages. The monocyte

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Published

2020-11-12

Issue

Section

Research Articles

How to Cite

1.
Molecular Docking Study on CD14 Receptor of Human Macrophage Cells by Screening Active Compounds Present in Clerodendrum Inerme. Int J of Pharm Chem [Internet]. 2020 Nov. 12 [cited 2025 Jul. 22];10(4):e5411. Available from: https://ssjournals.co.in/index.php/ijpc/article/view/5411