Phytochemical investigation and study on biological activities of flowers of Bombax ceiba
Phytochemical and biological investigation of flowers of Bombax ceiba
DOI:
https://doi.org/10.7439/ijpc.v10i2.5375Keywords:
Phytochemical, Phytochemical, Bombax ceiba L., Bombax ceiba L., cytotoxicity assay, cytotoxicity assay, antimicrobial screening, antimicrobial screening, antioxidant capacity, antioxidant capacity, antioxidant activity screening, antioxidant activity screening, brine shrimp lethality bioassay, brine shrimp lethality bioassayAbstract
Phytochemical investigations on the flowers of Bombax ceiba L. resulted in isolation and characterization of three compounds scopoletin, stigmastreol and palmitic acid. n-Hexane, chloroform, DCM, ethyl acid, aqueous and methanolic extract of B. ceiba flowers were made for screening different bioactivity such as cytotoxicity assay, antimicrobial screening, antioxidant capacity and activity screening, brine shrimp lethality bioassay. n-Hexane extract contained highest percentage of caprylic acid as both free and bound fatty acid. n-Hexane fraction showed low antibacterial activity against S. aureus and V. mimicus with zone of inhibition ranging from 0-10 mm. No fraction showed cytotoxicity against HeLa or vero cell line. In brine shrimp lethality bioassay, n-hexane and ethyl acetate extract showed strong cytotoxic potential than the positive control having LC50 values 2.91
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