A review on gastroretentive floating beads
DOI:
https://doi.org/10.7439/ijpc.v9i2.5128Keywords:
floating dosage form, floating dosage form, floating beads, floating beads, method of preparation, method of preparation, evaluation of beads, evaluation of beadsAbstract
The main aim of any drug delivery system is to bring about the desired concentration of the drug in blood or tissue, which is therapeutically effective and nontoxic for a prolonged period. The recent developments of FDDS are including the physiological and formulation variables affecting gastric retention, approaches to design single-unit and multiple-unit floating systems. Floating beads are used for controlled drug release as they have gastro retentive property without affecting the gastric emptying rate. Gastro retentive delivery systems can be retained in the stomach and assist in enhancing absorption and the bioavailability of drug which has a narrow absorption window in a particular region of gastrointestinal tract. This can be achieved by using various natural polymers.
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