Synthesis and antimicrobial evaluation of selected new benzimidazole-acetamido conjugates
DOI:
https://doi.org/10.7439/ijpc.v6i6.3292Keywords:
Organic synthesisAbstract
A simple and convenient syntheses and characterization of selected amino acid esters, 1,2,4-triazaoles, thiadiazoles and oxadiazoles in good yields using simple conditions are described. The antimicrobial activities of these new benzimidazole-acetamido conjugates are described.Downloads
References
K. Shah, S. Chhabra, S. K. Shrivastava, and P. Mishra, Med. Chem. Res. 2013, 22, 5077-5104.
M. Wang, X. Han, and Z. Zhou, Expert Opin. Ther. Patents 2015, 25, 595-611.
For some recent examples, see H. Thakuria, and G. Das, ARKIVOC 2008, xv, 321 and references cited therein.
P. P. Kattimani, R. R. Kamble and G. Y. Meti, RSC Advances 2015, 5, 29447-29455.
T. B. Nguyen, L. Ermolenko and A. Al-Mourabit, Synthesis 2015, 47, 1741-1748.
C. Chen, C. Chen, B. Li, J. Tao and J. Peng, J. Molecules 2012, 17, 12506-12520.
P. Ghosh and R. Subba, Tetrahedron Lett. 2015, 56 2691-2694.
A. A.-H. Abdel-Rahman, I. F. Nassar, I. M. H. El-Kattan, A. A. Aly, M. S. Behalo and N. A. M. Abdelwahed, Der Pharma Chemica, 2013, 5, 210-217.
J. Gowda, A. M. A. Khadar, B. Kalluraya and N. S. Kumari, Ind. J. Chem. 2010, 49B, 1130-1134 and references cited therein.
T. Curtius, J. Prakt. Chemie 1904, 70, 57-108.
A. A.-H. Abdel-Rahman, A. E.-S. Abdel-Megied, H. M. Abdel-Bary, A.-A. H. Abdel-Aleem, E. M. I. Morcy and M. T. Shabaan, Monatsh. Chem. 2009, 140, 559-564.
A recent modification on the Curtius rearrangement has been reported by H. P. Hemantha, G. Chennakrishnareddy, T. M. Vishwanatha and V. V. Sureshbabu, Synlett 2009, 3, 407-410 and references cited therein.
C. H. Moussebois, J. F. Heremans, P. Osinski and W. Rennerts, J. Org. Chem. 1976, 41, 1340-1343.
B. R. P. Kumar, M. Soni, S. S. Kumar, K. Singh, M. Patil, R. B. N. Baig, and L. Adhikary, Eur. J. Med. Chem. 2011, 46, 835-844.
W. H. Pirkle, D. L. Sikkenga and M. S. Pavlin, J. Org. Chem. 1977, 42, 384-387.
J. Jarusiewicz, Y. Choe, K. S. Yoo, C. P. Park and K. W. Jung, J. Org. Chem. 2009, 74, 2873-2876.
M. Yoshimura, N. Shibata, M. Kawakami and S. Sakaguchi, Tetrahedron 2012, 68, 3512-3518.
Y. Li, J. Geng, Y. Liu, S. Shenghu and G. Zhao, ChemMedChem 2013, 8(1), 27-41.
S. G. P. Kempgowda, P. Dev and M.T. Tamiz, Der. Pharma. Chem 2011, 3(2), 330-341.
R. Agrawal and S. S. Pancholi, Der Pharma Chem., 2011, 3 (6), 32-40.
S. Bajaj, V. Asati, J. Singh and P. P. Roy Eur. J. Med. Chem. 2015, 97 124-141.
W. Rzeski, J. Matysiak and M. Kandefer-Szerszen, Biororg. Med. Chem. 2007, 15, 3201-3207.
W. S. Hamama, M. A. Gouda, M. H. A. Abdel El-Wahab and H. H. Zoorob, J. Hetero. Chem. 2014, 51, 1558-1581.
J. G. Collee, J. P. Duguid, A. G. Fraser, B. P. Marmion and A. C. Scott, In Mackie and MacCartney Practical Medical Microbiology. 13th Ed. Vol. 2. London, UK: Churchill Livingstone; 1989.
A. Sadula, U. R. Peddaboina and P. N. J. Subhashini, Med. Chem. Res. 2015, 24, 851-859.
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