FT-IR Spectroscopic Assay Method for Eslicarbazepine Acetate in Bulk and Tablet Formulations

Authors

  • Ravi Prasad Indian Institute of Chemical Technology, Hyderabad
  • Bhuvaneswari Kotamarthi Indian Institute of Chemical Technology, Hyderabad
  • Rajani Kompally Indian Institute of Chemical Technology, Hyderabad
  • Anu Radha Indian Institute of Chemical Technology, Hyderabad

DOI:

https://doi.org/10.7439/ijpc.v5i7.2238

Keywords:

pcr, rflp

Abstract

A simple, precise and rapid FT-IR spectroscopic method has been developed for the quantification of Eslicarbazepine acetate (ECA) in bulk and tablet formulations. The method involves the measurement of absorbance of carbonyl (C=O) peak at 1726 cm-1 and evaluation of unknown drug component from the measured absorbance values using standard calibration plot. The method was validated as per ICH guidelines and successfully applied for the estimation of ECA in pharmaceuticals in tablet form.

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Author Biographies

  • Ravi Prasad, Indian Institute of Chemical Technology, Hyderabad

    Analytical Chemistry Division

  • Bhuvaneswari Kotamarthi, Indian Institute of Chemical Technology, Hyderabad

    Analytical Chemistry Division

  • Rajani Kompally, Indian Institute of Chemical Technology, Hyderabad
    Analytical Chemistry Division
  • Anu Radha, Indian Institute of Chemical Technology, Hyderabad
    Analytical Chemistry Division

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Published

2015-07-30

Issue

Vol. 5 No. 7 (2015): Jul

Section

Research Articles

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How to Cite

1.
FT-IR Spectroscopic Assay Method for Eslicarbazepine Acetate in Bulk and Tablet Formulations. Int J of Pharm Chem [Internet]. 2015 Jul. 30 [cited 2025 May 24];5(7):255-9. Available from: https://ssjournals.co.in/index.php/ijpc/article/view/2238
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