Synthesis, spectral, electrochemical and antibacterial studies of tetraaza macrocyclic complexes of Mn(II) and Co(II)

Abstract

Me ₂ dibenzo[ b,l ]dipyridyl[ g,q ][1,5,11,15]-tetraaza-6,10,16,20-tetraoxocycloeicosane macro-cyclic complexes of Mn(II) and Co(II) have been synthesized by the template method. These synthetic macrocycles analysed by various techniques like Molar conductance, FTIR, UV-Vis. and Mass spectra etc. Cyclic voltammetric studies were carried out on Pt disc (tip-06.1204.120.) electrode (2mm diameter) in different solvents. The heterogeneous electron transfer rate constant (K ⁰ ) was also determined with the help of Nicholson and Kochis method in MeOH, Acetonitrile (AN), DMF and found in the order K ⁰_MeOH >K ⁰_AN >K ⁰_DMF. The octahedral geometry have been assigned to these macrocycles and attributed the unusual oxidation state of metal ion which is stabilized by macrocyclic cavity. These synthetic macrocycles were also tested for their antibacterial activities against E. coli, P. aeruginosa, B. cereus, S. aureus and C. albicans bacteria to assess their inhibition potential and were compared with standard drugs like Gentamycin.