Determination of the stoichiometry and the association constant of a thiourea derivatives substrate-cyclodextrin complex

Authors

  • Fawaz El Omar Lebanese University Central Administration, Museum, Beirut - Lebanon
  • Ahmad Khodr Allouch Laboratory of Applied Chemistry (LAC), Faculty of Science III, Lebanese University, P.O. Box 826, Tripoli
  • Inas EL Hassan Laboratory of Applied Chemistry (LAC), Faculty of Science III, Lebanese University, P.O. Box 826, Tripoli
  • Hanna El Nakat Department of Chemistry, Faculty of Science, University of Balamand, P.O. Box 100, Tripoli,
  • Noha Ghanem Laboratory of Applied Chemistry (LAC), Faculty of Science III, Lebanese University, P.O. Box 826, Tripoli

DOI:

https://doi.org/10.7439/ijpc.v3i3.43

Abstract

The determination of stoichiometry and association constant of inclusion complex of N-(2-methylphenyl)-N'-(2-methylphenyl) thiourea with hydroxypropyl-b-cyclodextrin (HP-b-CD) by mean of UV-visible spectrophotometry has been investigated. The stoichiometry of the complex formed was determined by continuous variation (Job's plot) method and the overall association constant and its corresponding uncertainties were determined by using Scott's method.

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Published

2013-07-12

Issue

Vol. 3 No. 3 (2013): Jul- Sep

Section

Research Articles

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How to Cite

1.
Determination of the stoichiometry and the association constant of a thiourea derivatives substrate-cyclodextrin complex. Int J of Pharm Chem [Internet]. 2013 Jul. 12 [cited 2025 Jul. 4];3(3):45-9. Available from: https://ssjournals.co.in/index.php/ijpc/article/view/1307
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