Spectrophotometric Determination of Escitalopram in Pharmaceuticals

Authors

  • Khairia Mohammed Al-Ahmary King Abdulaziz University

DOI:

https://doi.org/10.7439/ijpc.v2i4.773

Abstract

A new, simple, fast and sensitive two spectrophotometric methods has been developed for determination of Escitalopram in bulk and tablet dosage forms. The method A is based on the oxidation of Escitalopram by a known excess of bromate-bromide mixture in hydrochloric acid medium, reduction of the residual oxidant by a fixed amount of iron(II) and the formation of iron(III)-thiocyanate-complex which is measured at 480 nm. In the method B, 1,10-phenanthroline is used as a complexing agent and the formation of iron(II)-1,10-phenanthroline, which is measured at 510 nm.

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Author Biography

  • Khairia Mohammed Al-Ahmary, King Abdulaziz University
    Analytical chemistry

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Published

2013-01-01

Issue

Section

Research Articles

How to Cite

1.
Spectrophotometric Determination of Escitalopram in Pharmaceuticals. Int J of Pharm Chem [Internet]. 2013 Jan. 1 [cited 2025 Jun. 8];2(4):121-5. Available from: https://ssjournals.co.in/index.php/ijpc/article/view/1296