FLOW INJECTION DETERMINATION OF SALBUTAMOL USING A SOLID-PHASE REACTOR CONTAINING LEAD (IV) DIOXIDE IMMOBILIZED
DOI:
https://doi.org/10.7439/ijpc.v2i3.701Abstract
A very simple, sensitive and fast continuous flow injection system with spectrophotometric detection was proposed for the determination of salbutamol sulphate (SAL) in pharmaceutical formulations using a solid-phase reactor containing PbO2 immobilized in a polymeric matrix. The method was based on oxidation of the reagent (N, N-dimethyl-p-phenelynediamine) with PbO2 producing dimethylbenzoquinone diimine, which is then coupling with SAL in alkaline medium .The blue colored product was monitored at 640 nm. The calibration graph was linear over the range 0.5-60 ?g mL-1 with a relative standard deviation less than 3.8% (n=33) and sample throughput 60 samples h-1.Downloads
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Published
2012-10-01
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Research Articles
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How to Cite
1.
FLOW INJECTION DETERMINATION OF SALBUTAMOL USING A SOLID-PHASE REACTOR CONTAINING LEAD (IV) DIOXIDE IMMOBILIZED. Int J of Pharm Chem [Internet]. 2012 Oct. 1 [cited 2026 Feb. 16];2(3):61-6. Available from: https://ssjournals.co.in/index.php/ijpc/article/view/1287
