REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF ARTESUNATE IN TABLET DOSAGE FORM

Authors

  • S. C. Kale 1K. Y. D. S. C. T`s College of Pharmacy, Sakegaon, Tal Bhusawal, Dist. Jalgaon
  • M. S. Palled Department of Pharmaceutical Chemistry, K.L.E.S's College of Pharmacy, Belgaum, Karnataka
  • A. R. Bhat Department of Pharmaceutical Chemistry, K.L.E.S's College of Pharmacy, Belgaum, Karnataka
  • M. K. Kale 1K. Y. D. S. C. T`s College of Pharmacy, Sakegaon, Tal Bhusawal, Dist. Jalgaon
  • Ritesh Bathe NRI Institute of Pharmacy, Bhopal (M.P)

DOI:

https://doi.org/10.7439/ijbar.v2i3.27

Abstract

Artesunate is a new potent antimalarial drug and is a synthetic analogue of artemisinin. A simple, economical, fast, and precise reverse phase high performance liquid chromatographic
method has been developed for the determination of Artesunate in tablet dosage form. The present method was developed on C-18 Hypersil (5 micron 25 cm× 4.6 mm) column, in isocratic mode with mobile phase acetonitrile: methanol (70: 30 v/v) at a constant flow rate of 1.0 ml/min and the detection wavelength was 211 nm. Proposed method was validated for precision, accuracy, linearity range, recovery, robustness and ruggedness. The developed method can be used for assay of Artesunate in pharmaceutical preparations.

Downloads

Download data is not yet available.

Downloads

Published

2011-04-01

Issue

Vol. 2 No. 3 (2011): Mar

Section

Original Research Articles

License

Authors who publish with this journal agree to the following terms:

  • Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  • Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  • Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeThe Effect of Open Access).

How to Cite

REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF ARTESUNATE IN TABLET DOSAGE FORM. (2011). International Journal of Biomedical and Advance Research, 2(3), 117-123. https://doi.org/10.7439/ijbar.v2i3.27
Crossref
Scopus
Google Scholar
Europe PMC