Comparative study of Left Ventricular Mass Index (LVMI) between Prehypertensives and Normotensives.

Abstract

Background : The aim of present study is to compare left ventricular mass index between prehypertensives and normotensives. Material and Methods : Total 100 Male subjects were selected from general population with the age range between 18 to 40 years and BMI range >18 Kg/m² to 30 Kg/m². Blood pressure were measured with mercury sphygmomanometer and prehypertension was classified according to JNC 7. 50 subjects were prehypertensives and 50 were normotensives. Two-dimensionally guided M-mode echocardiography was performed by standard methods using a 7340 ESAOTE echocardiograph. Left ventricular internal dimension (LVID) and interventricular septal and posterior wall thickness (IVST and PWT) were measured at end-diastole and end-systole. Left ventricular mass index (LVMI) was calculated at end-diastole by using the American Society of Echocardiography (ASE) convention. Statistical analysis was done using independent students t test. Results : Statistical analysis shows significant increase in LVMI in prehypertensive than normotnesives. (p value 0.05) Conclusion : LVMI is the indicator of target organ damage. From this study it is seen that LVMI is higher in prehypertensives than normotensives. Prehypertensive are more prone to converted into hypertensives. Thats why echocardiography is also recommended for prehypertensives to prevent cardiovascular morbidity and mortality.