Effect of aging on various haematological parameters

Abstract

Background : The present study was done to find out the significant changes in various haematological parameters with advancing age, both in males and females. Material and methods: The prospective cross sectional study was conducted in the Physiology Department in collaboration with Pathology Department at M.P Shah Govt Medical College, Jamnagar, Gujarat with sample size of 103 in the age group of 20 to 89 years. Out of these, 53 were males and 50 were females. Haematological parameters were measured by automated cell counter. Result: Our result showed that most of the haematological parameters decrease significantly in males after fifth decades. In females, the changes were not significant in most of the haematological parameters. Conclusion: Non significant changes of haematological parameters in females might have some hormonal correlation. Poor nutrition resulting in vitamin B₁₂ and folic acid deficiency in old age might be the cause of early haematologial changes and early aging. Further study with large sample size may reveal more information.