Reference interval of fasting plasma glucose and glycated haemoglobin in children in Port Harcourt Rivers State Nigeria
DOI:
https://doi.org/10.7439/ijbar.v10i11.5294Keywords:
Glycated Haemoglobin, Chromatography, Reference IntervalAbstract
Background: Studies have shown an increase in the prevalence of diabetes mellitus in children and a significant difference in the age- specific means of fasting plasma glucose and this has made it necessary to determine the local reference intervals of fasting plasma glucose and glycated haemoglobin in children in Port Harcourt and compare this with the reference interval of adults.
Method: 160 apparently healthy children between the ages of 7-10 years were recruited for this study. 2ml of blood was collected into fluoride oxalate bottles and EDTA bottles. These were later analyzed for glucose and glycated haemoglobin using the glucose oxidase method and Boronate chromatographic method, respectively.
Results: Reference interval of fasting plasma glucose was 3.1-5.7mmol/L and that of glycated haemoglobin was 4.0-5.1%, while those of adults for this same locality was 3.4-5.8mmol/l for FPG and 4.0-5.9% for glycated haemoglobin.
Conclusion: From the reference intervals of glycated haemoglobin and fasting plasma glucose so determined in this study, it may be unnecessary to have age specific reference intervals for fasting plasma glucose while that of glycated haemoglobin may need to be reviewed.
Downloads
Downloads
Published
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeThe Effect of Open Access).
How to Cite
