Comparison of Intubating Conditions after Administration of Rocuronium with That of Suxamethonium
DOI:
https://doi.org/10.7439/ijbar.v10i6.5207Keywords:
Intubation, General anaesthesia, Rocuroniu, Suxamethonium, Thiopentone, Laryngoscopy, OxygenAbstract
Background: Rapid and safe endotracheal intubation are of paramount importance in general anaesthesia. Rocuronium was shown to have the fastest onset of action of all currently available non-depolarizing neuromuscular blocking drugs and to provide intubating conditions similar to those of suxamethonium within 60 seconds after administration. Hence the present study was under taken to evaluate and compare the effects of Rocuronium and Suxamethonium with respect to the onset of action, intubating conditions, duration of action, haemodynamic effects and side effects.
Method: Total 80 patients were enrolled and divided into two groups of 40 patients in each. All patients were induced with Inj. Thiopentone 5mg/kg after preoxygenating with 100% oxygen. Group I received inj Rocuronium 0.6mg/kg and group II received Suxamethonium 1.5mg/kg. Patients were ventilated with 100% oxygen for 60 seconds, at the end of 60 seconds laryngoscopy was performed and intubating conditions were graded.
Results: Rocuronium produced clinically acceptable i.e. excellent and good intubating conditions in 33 patients (82.5%) at 60 sec. while Suxamethonium produced clinically acceptable intubating conditions in 37 patients (92.5%). The mean onset of action of Rocuronium and Suxamethonium was 81.07
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