Non-invasive predictors of esophageal varices in patients with cirrhosis of liver
DOI:
https://doi.org/10.7439/ijbar.v10i4.5161Keywords:
Esophageal varices, Cirrhosis, Liver, Spleen, Diameter, Sensitivity, Thrombocytopenia, EndoscopyAbstract
Background: Cirrhotic patients commonly undergo screening endoscopy for the existence of esophageal varices (EVs). Several studies have evaluated possible noninvasive markers of EVs to reduce the number of unnecessary endoscopies in patients with cirrhosis but without varices. Aim of the present study was to identify and analyze clinical, biochemical, ultrasonographic predictors of EVs in cirrhotic patients and correlate these predictors with endoscopic findings.
Method: Total hundred newly diagnosed cirrhotic patients of aged ?18 without prior history of gastrointestinal bleeding were subjected to clinical evaluation, biochemical workup, esophagogastroduodenoscopy, and ultrasonographic measurement of spleen bipolar diameter and ascites. Non-invasive parameters were assessed and platelet count (PC)/spleen diameter (SD) ratio was calculated for all patients.
Results: Out of 100 patients, 80 (80%) were found to have esophageal varices. The incidence of grade I (33%) and grade II (34%) varices predominate. Majority of patients belonged to Child-pugh class C (68%) followed by class B (28). Mean PC and SD among patients with varices was 115300
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