Prevalence and Antibiotic profile of Non fermenters at tertiary care hospital, Surat
DOI:
https://doi.org/10.7439/ijbar.v9i9.4890Keywords:
Non fermenters, Prevalence, antibiotic susceptibility testingAbstract
Introduction: Non fermenters are omnipresent in nature like soil, water, plants, decaying vegetations, food stuffs and normal flora of human. Their pathogenic potential has been well established by their frequent isolation from clinical samples and their association with clinical diseases. In last few years problem is increased by the emergence of resistance to antimicrobial agents which are widely used against the non fermenters, making them as an important health care associated pathogen.
Objectives: To see prevalence and antibiotic susceptibility of non fermenters in tertiary care hospital, Surat to guide health care management.
Methods: It was a prospective observational analytical study in which patients with isolated non fermenters from various clinical samples received by Microbiology department were enrolled. Samples were processed according to standard guidelines. Isolates were identified with different biochemical reactions and antibiotic susceptibility testing was performed on Muller hinton agar by Kirby bauer disc diffusion method. The results were interpreted according to CLSI guidelines 2017.
Results: Total 157 isolates were obtained. A. baumannii was the most common organism isolated followed by P. aeruginosa . The mean age group was 15-29 years with male preponderance. The sensitivity showed complete sensitivity to only Polymyxin group of drugs with 2nd highest sensitive group Carbapenems.
Conclusions: The present study highlighted the fact that non fermenter gram negative bacilli are emerging as important pathogens and shows resistance to commonly used antibiotics, so rapid identification should be done for appropriate patient care.
Downloads
References
Washington W, Stephen A, William J; Koneman's Color Atlas and textbook of Diagnostic Microbiology; 6th Edition; Ch-7; pg-303-91.
Bhargava D, Kar S, Saha M. Original Research Article Prevalence of Non-Fermentative Gram Negative Bacilli Infection in Tertiary Care Hospital in Birgunj , Nepal. Int J Curr Microbiol Appl Sci. 2015; 4(7):301-7.
Rani PU, Vijayalakshmi P. Epidemiological Pattern of Non-fermenting Metallo Beta Lactamase Producing Bacterial Pathogens Isolated from Clinical Specimens in a Tertiary Care Hospital in Kakinada, India. Microbiology Research Journal International 2017; 18(3):1-10.
The Clinical and Laboratory Standards Institute. M100S Performance Standards for Antimicrobial Susceptibility Testing. 2017.
Padmavathy M, Malini J, Naveneeth B V. Prevalence of non-fermenting Gram-negative bacilli and their in vitro susceptibility pattern at a tertiary care teaching hospital. J Sci Soc 2014; 41(3):162-6.
Malini A, Deepa E, Gokul B, Prasad S. Nonfermenting gram-negative bacilli infections in a tertiary care hospital in Kolar, Karnataka. J Lab Physicians. 2009; 1(2):62-6.
Bruno D, Nishino MK, Priore WN, Remus PR, do Carmo AA, Stefanello VB, et al. Prevalence of Gram-negative non-fermenters patients in Porto Alegre-RS. Jornal Brasileiro de Patologia e Medina Laboratorial 2011; 47:529-34.
Gupta V, Chhina D, Kaur A. Incidence of metallo-beta-lactamase (MBL) producing nonfermenters isolated from respiratory samples in ICU patients. Int J Pharm Bio Sci 2013; 4: 580-5.
Wadhwa R, Sharma Y, Upadhyay RP, Bala K. Nosocomial infection by non-fermenting gram negative bacilli in tertiary care hospital: Screening and cure. Int J Pharm Pharm Sci. 2016; 8(3):274-7.
Patel PH, Pethani JD, Rathod SD, Bimal C, Shah PD. Prevalence of nonfermenting Gram negative bacilli infection in tertiary care Hospital in Ahmedabad, Gujarat. Indian J Basic Appl Med Res. 2013; 2(6):60813.
Thipperudraswamy T, Sudhindra.K, Shobha Nadigar, Mahesh Kumar. Prevalence of nonfermenting gram negative bacilli from clinical isolates and their antibiogram. 2014; 3(2):55-61.
Rit K, Nag F, Raj HJ, Maity PK. Prevalence and Susceptibility Profiles of Nonfermentative Gram-negative Bacilli Infection in. Indian J Clin Pract. 2013; 24(5):451-5.
Vishwanath S, Munim F, Chawla K. Nonfermenting gram-negative bacilli other than pseudomonas aeruginosa and acinetobacter spp. causing respiratory tract infections in a tertiary care center. J Glob Infect Dis. 2013; 5(4):144-8.
Samanta P, Gautam V, Thapar R, Ray P. Emerging resistance of non-fermenting gram negative bacilli in a tertiary care centre Classical Burkitt's lymphoma. 2011; 54(3):666-7.
Downloads
Published
Issue
Section
License
Copyright (c) 2018 International Journal of Biomedical and Advance Research

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeThe Effect of Open Access).