HYPOLIPIDEMIC ACTIVITY OF ETHANOLIC EXTRACT OF DAUCUS CAROTA SEEDS IN NORMAL RATS

Authors

  • Kamlesh Singh Shri Rawatpura Sarkar Institute of Pharmacy, Kumhari, Durg, (C.G)
  • Hemant Dhongade Shri Rawatpura Sarkar Institute of Pharmacy, Kumhari, Durg, (C.G)
  • Nisha Singh Shri Rawatpura Sarkar Institute of Pharmacy, Kumhari, Durg, (C.G)
  • Pranita Kashyap Shri Rawatpura Sarkar Institute of Pharmacy, Kumhari, Durg, (C.G)

DOI:

https://doi.org/10.7439/ijbar.v1i3.4

Keywords:

Foleys catheter, clog, flush

Abstract

Objective: Hypolipidemic activity of ethanolic extract of Daucus carota seeds in Normal rats.
Method: Rats were divided in to 4 groups. First control group, treated with vehicle only for 7 days. Second group was standard, treated with lovastatin (7.2mg/kg) for 7 days. Third and fourth group were test, treated with Daucus carota seeds extract (200mg/kg and 400mg/kg) for 7 days. 8th day blood sample was collected by retro orbital route and lipid profiles were estimated in serum.
Result and Conclusions: Standard and test (400mg/kg DCSE) groups were showed significant (P 0.001) reduction in the total cholesterol, triglyceride HDL and VLDL as compared control group. Test group (200mg/kg) was showed significant (P 0.05) reduction as compared control group. The antioxidant potential of Daucus carota seeds has contributed to the reduction of oxidative stress and Lipid levels in experimental rats.

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Published

2010-11-01

Issue

Vol. 1 No. 3 (2010): Oct

Section

Original Research Articles

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How to Cite

1.
HYPOLIPIDEMIC ACTIVITY OF ETHANOLIC EXTRACT OF DAUCUS CAROTA SEEDS IN NORMAL RATS. Int J of Biomed & Adv Res [Internet]. 2010 Nov. 1 [cited 2024 Sep. 8];1(3):73-81. Available from: https://ssjournals.co.in/index.php/ijbar/article/view/43