Comparison and detection the level of C Reactive Protein in different age groups on patients of Rheumatoid Arthritis at tertiary care centre of Kanpur (U.P.)

Abstract

Background: C-reactive protein (CRP) is a phylogenetically highly conserved plasma protein, with homologous in vertebrates and many invertebrates that participate in the systemic response to inflammation. So the significance of this study is to detect the levels of CRP in RA patients and its association with different age groups. Objectives: 1. To detect the levels of CRP in RA patients. 2. To compare the CRP levels in different age groups. Material and Methods: A hospital based study was conducted among 180 rheumatoid arthritis patients who attended the medicine OPD in 1 year. A predesigned questionnaire was used to collect the particulars of the patient. 5ml blood sample was collected from patients after informed consent. CRP levels were detected by semi-quantitative method. Appropriate statistical methods were used for defining the objectives. Epi info software was used for analysis purpose. Results: as the age increases the CRP levels increases (2.960.816, CI= 2.78-3.14) for the age group of 20-40 years. And (3.120.932, CI= 3.02-3.39) for 41-60 and above. Also the level of CRP increases it is considered only in mild category. Conclusion: Proper investigation during the signs and symptoms must be done. As CRP increases with age all the necessary prevention and diagnostic techniques must be used.