A comparative study on renal function parameters and age in females with and without pre-eclampsia in a tertiary health care setup

Abstract

Background and objective: Pathogenesis of preeclampsia is known to be associated with renal dysfunction. But the best suited renal function parameter to quantify pathogenesis of this clinical condition is unclear. This study is aimed to assess the renal parameters in preeclampsia. Materials and Methods: 185 consecutive mothers in 20th week of gestational period were enrolled into the study. Based on the presence or absence of preeclampsia they were divided into two subgroups: Group A (82 mothers with preeclampsia) and Group B (103 normotensive mothers). Results: In all the mothers serum urea, serum creatinine and serum uric acid was measured. Serum uric acid of group A was very significantly higher compared to group B ( p 0.0001). Serum urea and serum creatinine of group A was just significantly higher compared to group B (p 0.05). Conclusions: Among the renal function parameters measured uric acid was better suited in assessing renal dysfunction in mothers with preeclampsia.