Medical management of unruptured ectopic pregnancy by methotrexate: A five years experience at tertiary care hospital

Authors

  • Anil Munemane Associate Professor, Department of Pathology Rural Medical College Loni, Maharashtra
  • Manisha Munemane Senior Consultant, OBGY Aditya Birla Memorial Hospital Chinchwad, Pune. Maharashtra

DOI:

https://doi.org/10.7439/ijbar.v4i10.491

Abstract

Background: Medical treatment of ectopic pregnancy with methotrexate has been considered as an alternative to surgical intervention. Aims and objectives: The present was carried with an aim to determine the role of methotrexate in management of ectopic pregnancy. Materials and methods: The present study was carried out for a period of 5 years (September 2007 to August 2012) in a tertiary care hospital. It included a total of 128 patients of unruptured ectopic pregnancies. The medical management was done with methotrexate. Time taken for complete β human chorionic gonadotrophin (β hCG) resolution was recorded. The negative β hCG result indicated as an endpoint of successful outcome. Results: Out of 128 cases where Methotrexate was used, 4 required surgery. In remaining 124 cases, there were no side effects. Complete β hCG resolution was achieved in 28 -35 days. Subsequent tubal patency and reproductive functions were comparable to that of surgical management. Conclusion: From our study, it can be concluded that methotrexate can be recommended as safe and effective drug for management of unruptured ectopic pregnancies.

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Published

2013-10-30

Issue

Section

Original Research Articles

How to Cite

Medical management of unruptured ectopic pregnancy by methotrexate: A five years experience at tertiary care hospital. (2013). International Journal of Biomedical and Advance Research, 4(10), 695-697. https://doi.org/10.7439/ijbar.v4i10.491