Aggressive Angiomyxoa of Vulva: Wide local excision case report

Abstract

Aims and Background: Aggressive angiomyxoma is rare tumor of pelvic and perineal organs, occurring usually in women of reproductive age, and carrying a high tendency to local infiltration and relapse. It is non-malignant but can be locally aggressive and frequently recurs. Misdiagnosis is frequent. Wide excision is the preferred method of treatment but the challenge is to perform the degree of extirpation necessary to prevent recurrence. Most literature about Aggressive angiomyxoma consists of isolated case reports. Presentation of Case: We reported a case of 35-year-old Indian woman complaining of a slow and progressive growth of a left vulvar labia major a pedunculated tumor with long a stalk was detected second time after first resection 2yrs back, measuring of 15.0x8.0 cm. Wide local surgical resection of the tumor were performed. Histopathology diagnosed a large aggressive angiomyxoma with uninvolved resection margins. Patient remains without recurrence at 8.0-months follow up. Discussion and Conclusion: Non Aggressive angiomyxomais rare but should be excluded in any large vulval mass. We expect that awareness accompanied with wide free safe margin excision has important role to prevent the recurrence of tumor.