Serological study of Leptospirosis in central Nepal
DOI:
https://doi.org/10.7439/ijbar.v4i7.419Keywords:
Azezo, Ethiopia, Treatment outcome, TuberculosisAbstract
Background: Leptospirosis, an infectious disease caused by spirochetes of the genus Leptospira, is the most widespread zoonosis in the world. Humans acquire infection through contact with the urine of infected or carrier animals, either directly or through contaminated water or soil. There are only few reports documenting the serological evidence of leptospirosis in Nepal. Thus, present study aims to determine the status of leptospirosis in central Nepal. Material and Methods: A descriptive cross sectional study was conducted in 1266 patients suspected of leptospirosis in Chitwan Medical College Teaching Hospital for a period of two years. Blood samples collected from the patients were processed for qualitative detection of leptospiral IgM antibody by ELISA (Enzyme linked immunosorbent assay). Results: Of the 1266 samples subjected to ELISA, seropositivity was seen in 61 samples (4.8%) with the highest rate observed in the autumn season (63.9%) followed by summer season (21.3%). Majority (39.3%) of the seropositive individuals were agricultural workers. Leptospirosis was more common in males and in the people of 16-30 years. Conclusion: Leptospirosis is common in central Nepal. Epidemiological surveillance and laboratory capacity across the region need strengthening to determine its true prevalence in the community.Downloads
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Published
2013-07-18
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Serological study of Leptospirosis in central Nepal. Int J of Biomed & Adv Res [Internet]. 2013 Jul. 18 [cited 2024 Oct. 18];4(7):455-9. Available from: https://ssjournals.co.in/index.php/ijbar/article/view/339