The influence of blood glucose level upon the transport of light in diabetic and non-diabetic subjects

Abstract

The present paper describes the influence of blood glucose concentrations up on the light transport pattern and to detect the feasibility of this principle for noninvasive blood glucose measurement. The characteristics of the blood glucose molecules to influence the optical signal transportation have been investigated and calculated by utilizing the mathematical parameters on the resultant output signal. Investigational studies on non-diabetic and diabetic subjects reveal that blood glucose concentrations have empirical relationship over light transport phenomenon in the biological tissues. When blood glucose levels increases, the optical property of the biological tissue changes, causing lower distribution patterns, accordingly the optical light path is reduced. Furthermore, variation in the optical light path relating to blood glucose concentrations is very weak in nature. To overcome this difficulty, in our pilot study, amplitude modulated ultrasound and infrared techniques have been utilized. The output signal results of this hybrid noninvasive technology for the measurement of blood glucose levels are promising in nature. It can be employed for the design and development of the noninvasive blood glucometer.