A study of pattern of secretion of salivary melatonin in shift workers
DOI:
https://doi.org/10.7439/ijbar.v6i10.2551Keywords:
Pap smear, Rural women, Neoplasia, Cervical infections, ProfileAbstract
Background: Globalization and industrialization lead round the clock service providers (shift workers) vulnerable for circadian rhythm sleep disorders Aim and Objective: To know how effect of shift work on secretory pattern of melatonin in saliva since there is growing evidence that antioxidant characteristic of melatonin may be reason for development of cancer in long standing shift workers in future. Materials and Method: The study was observational, controlled, parallel study carried out in 30 shift workers (mean [SD] age: 21.33 [0.48] years) and 30 age matched healthy subjects (mean [SD] age: 24.97 [2.55] years). Saliva samples for the measurement of melatonin totally were collected from participants resting in dim light at 2 hr min intervals between 20:00 and 00:00 h. Result: A decreasing time line trend of salivary secretion of melatonin was observed for shift workers. Conclusion: The circadian phase is altered in shift workers as compared to day workers using salivary melatonin concentration as a marker of the circadian phase.Downloads
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