Magnesium supplementation during cardiopulmonary bypass to prevent junctional ectopic tachycardia after pediatric TOF surgery A randomized controlled study

Authors

  • Mrugesh Prajapati Assistant Professor Department of Cardiac Anesthesia U. N. Mehta Institute of Cardiology and Research Center, (Affiliated to B. J. Medical College), New Civil Hospital Campus, Asarwa, Ahmedabad-380016, Gujarat
  • Jigar Patel Assistant Professor Department of Cardiac Anesthesia U. N. Mehta Institute of Cardiology and Research Center, (Affiliated to B. J. Medical College), New Civil Hospital Campus, Asarwa, Ahmedabad-380016, Gujarat
  • Himani Pandya Research Associate Department of Research U. N. Mehta Institute of Cardiology and Research Center, (Affiliated to B. J. Medical College), New Civil Hospital Campus, Asarwa, Ahmedabad-380016, Gujarat
  • Hasmukh Patel DM Resident Department of Cardiac Anesthesia U. N. Mehta Institute of Cardiology and Research Center, (Affiliated to B. J. Medical College), New Civil Hospital Campus, Asarwa, Ahmedabad-380016, Gujarat

DOI:

https://doi.org/10.7439/ijbar.v6i8.2362

Keywords:

Modified WHO Partograph, Labor and Delivery

Abstract

Objective: The occurrence of postoperative junctional ectopic tachycardia (JET) is more frequent in certain types of congenital heart surgery. Magnesium decreases the incidence of junctional ectopic tachycardia after surgery. Therefore we prospectively examined the effect of magnesium treatment on the incidence of postoperative JET in pediatric patients undergoing surgical repair of congenital heart defects. Methods and results: We performed a randomized, double-blind, controlled study in 90 pediatric patients. Magnesium sulfate (MgSO4) or placebo was administered during the rewarming phase of cardiopulmonary bypass: group 1, placebo group (30 patients); group 2, 25 mg/kg of MgSO4 (30 patients); and group 3, 50mg/kg of MgSO4(30 patients). The overall incidence of JET was 11.1%. Group 1 patients had higher proportion of JET 6 (20%), than group 2 and group 3 (10 %, 3.3%). Conclusions: Supplementation with MgSO4 during cardiopulmonary bypass seems to reduce the incidence of hypomagnesemia and junctional ectopic tachycardia at admission to the cardiac intensive care unit. This effect seems to be dose related.

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Published

2015-08-30

Issue

Vol. 6 No. 8 (2015): Aug

Section

Original Research Articles

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How to Cite

Magnesium supplementation during cardiopulmonary bypass to prevent junctional ectopic tachycardia after pediatric TOF surgery A randomized controlled study. (2015). International Journal of Biomedical and Advance Research, 6(8), 584-588. https://doi.org/10.7439/ijbar.v6i8.2362
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