A Study Of The Clinical and Biochemical Profile Of Acute Viral Hepatitis

Authors

  • Varsha Shirish Dabadghao Associate Professor, Department of Medicine, Dr D.Y.Patil Medical College,Hospital and Research Centre, Pimpri, Pune-411018
  • Ram Barure Junior resident,Department of Medicine Dr D.Y.Patil Medical College,Hospital and Research Centre, Pimpri, Pune-411018
  • Suresh Kumar Sharma Professor, Department of Medicine Dr D.Y.Patil Medical College,Hospital and Research Centre, Pimpri, Pune-411018
  • Sangram Mangudkar Assistant Professor,Department of Medicine Dr D.Y.Patil Medical College,Hospital and Research Centre, Pimpri, Pune-411018

DOI:

https://doi.org/10.7439/ijbar.v6i10.2350

Abstract

Aim: This study was performed to compare the clinical, biochemical and etiological properties of acute viral hepatitis (AVH) and to compare clinical and laboratory parameters of faeco-oraly transmitted hepatitis: hepatitis A+ hepatitis E (A+E) with hematologicaly transmitted: hepatitis B, C, D (B+C+D) hepatitis. Material and Methods: Biochemical and clinical data were collected from 40 patients with AVH. They were tested for hepatitis B surface antigen (HBsAg), IgM anti-Hepatitis A virus (HAV), IgM anti-HBc (hepatitis B core antigen), IgM anti- hepatitis D (HDV), or IgM anti- hepatitis C (HCV). Finally X2 test was used to analysis of data. Results: Most patients were young adults and presented with jaundice and other constitutional features, although anicteric hepatitis was also seen. Hepatitis E was the most common AVH. Malaise, fever, icterus, vomiting and nausea were significantly more in Hepatitis A +E compared with Hepatitis B + C in acute course. Serum bilirubin both total and direct was significantly elevated in hepatitis A + E compared with Hepatitis B + C in acute course. Conclusions: Hepatitis E was the most common AVH .There were some differences in clinical and laboratory findings regarding to the etiology but it does not necessarily distinguish one cause of hepatitis from another.

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Author Biographies

  • Varsha Shirish Dabadghao, Associate Professor, Department of Medicine, Dr D.Y.Patil Medical College,Hospital and Research Centre, Pimpri, Pune-411018
    Associate Professor, Department of Medicine

    Dr D.Y.Patil Medical College,Hospital and Research Centre,
    Pimpri,
    Pune-411018

  • Ram Barure, Junior resident,Department of Medicine Dr D.Y.Patil Medical College,Hospital and Research Centre, Pimpri, Pune-411018
    Junior resident,Department of Medicine

    Dr D.Y.Patil Medical College,Hospital and Research Centre,
    Pimpri,
    Pune-411018

  • Suresh Kumar Sharma, Professor, Department of Medicine Dr D.Y.Patil Medical College,Hospital and Research Centre, Pimpri, Pune-411018

    Professor,Department of Medicine
    Dr D.Y.Patil Medical College,Hospital and Research Centre,
    Pimpri,
    Pune-411018

  • Sangram Mangudkar, Assistant Professor,Department of Medicine Dr D.Y.Patil Medical College,Hospital and Research Centre, Pimpri, Pune-411018
    Assistant Professor,Department of Medicine

    Dr D.Y.Patil Medical College,Hospital and Research Centre,
    Pimpri,
    Pune-411018

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Published

2015-10-30

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Section

Original Research Articles

How to Cite

A Study Of The Clinical and Biochemical Profile Of Acute Viral Hepatitis. (2015). International Journal of Biomedical and Advance Research, 6(10), 689-694. https://doi.org/10.7439/ijbar.v6i10.2350