DYNAMIC IMAGING OF INTRACELLULAR CA2+ CONCENTRATION IN INSULIN SECRETING MIN6 Β-CELLS USING WIDE FIELD AND TIRF MICROSCOPY

Authors

  • Shiv Kumar Mishra School of Biotechnology Rajiv Gandhi proudyogiki vishwavidyalaya (RGPV) University of Technology of Madhya Pradesh Airport Bypass Road, Gandhi Nagar, Bhopal
  • Priyanka Sharma School of Biotechnology Rajiv Gandhi proudyogiki vishwavidyalaya (RGPV) University of Technology of Madhya Pradesh Airport Bypass Road, Gandhi Nagar, Bhopal
  • Vinita Pawar School of Biotechnology Rajiv Gandhi proudyogiki vishwavidyalaya (RGPV) University of Technology of Madhya Pradesh Airport Bypass Road, Gandhi Nagar, Bhopal
  • Archana Tiwari School of Biotechnology, Rajiv Gandhi proudyogiki vishwavidyalaya (RGPV, University of Technology of Madhya Pradesh, Airport Bypass Road, Gandhi Nagar, Bhopal

DOI:

https://doi.org/10.7439/ijbar.v3i10.327

Keywords:

Profunda femoris artery, Medial circumflex femoral artery, Lateral circumflex femoral artery

Abstract

Since 1920's major medical advance based on animal research i.e. Insulin for diabetes. Diabetes is world most common metabolic disorder characterised by pancreatic β-cells dysfunction. Normally these cells respond to high glucose concentrations following exocytosis of stored insulin trigger by the combined action of store-operated calcium entry (SOCE) and calcium-release activated current (CRAC) channel, with an elusive mechanism. To illustrate it, dynamic imaging may used as power full tool as, it offers power of capturing the dynamics of biological action in live cells. In this review we focuses on dynamic imaging of pancreatic MIN6 cells, an appropriate

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Published

2012-11-01

Issue

Vol. 3 No. 10 (2012): Oct

Section

Review Article

License

Copyright (c) 2012 International Journal of Biomedical and Advance Research

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How to Cite

DYNAMIC IMAGING OF INTRACELLULAR CA2+ CONCENTRATION IN INSULIN SECRETING MIN6 Β-CELLS USING WIDE FIELD AND TIRF MICROSCOPY. (2012). International Journal of Biomedical and Advance Research, 3(10), 747-752. https://doi.org/10.7439/ijbar.v3i10.327
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