NON HOGDKIN LYMPHOMA ASSOCIATED WITH SCHISTOSOMAISIS ? A CASE REPORT AND THE SIGNIFICANCE OF TUMOUR MARKERS

Authors

  • James O. Adisa Department of Medical Laboratory Science, University of Jos, P.M.B. 2084, Jos, Nigeria.
  • Ejike C. Egbujo Department of Medical Laboratory Science,University of Jos, Nigeria
  • Jonathan U. Madukwe National Hospital Abuja
  • Olugbenga A. Silas Pathology Department Jos University Teaching Hospital (JUTH), Jos
  • Godwin O. Echejoh Pathology Department Jos University Teaching Hospital (JUTH), Jos
  • Filimon H. Golwa Plateau State Specialist Hospital, Jos
  • Joseph M. Chundusu Plateau State Specialist Hospital, Jos
  • Amina Yahaya B. Pathology Department Jos University Teaching Hospital (JUTH), Jos

DOI:

https://doi.org/10.7439/ijbar.v3i9.672

Abstract

We report a case of a possible association of schistosomiasis with Non-Hodgkins lymphoma. A 19 year old Nigerian lady presented with week long history of abdominal swelling and vomiting. Sonography of the abdominal cavity gave a diagnosis of colonic tumour. Resected portion of the ileum showed an ileoceacal mass appearing like an intususception. Histopathology initially revealed schistosomal ova and the adult worm in-copula, Immunohistochemistry however revealed that the mass was not just a granuloma, but a diffuse B-lymphocyte Non-Hodgkins lymphocytic lymphoma. The proximity of the schistosoma ova in the tissue sections suggests that schistosomiasis may have some effect on carcinogenesis. We therefore recommend that patients with chronic parasitic infestation, especially schistosomiasis, should be monitored more closely in view of the relevant emerging association between cancer and infections.

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Author Biography

  • James O. Adisa, Department of Medical Laboratory Science, University of Jos, P.M.B. 2084, Jos, Nigeria.
    Senior Lecturer, Department of Medical Laboratory Science, University of Jos.

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Published

2012-10-01

Issue

Vol. 3 No. 9 (2012): Sep

Section

Case Report

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How to Cite

NON HOGDKIN LYMPHOMA ASSOCIATED WITH SCHISTOSOMAISIS ? A CASE REPORT AND THE SIGNIFICANCE OF TUMOUR MARKERS. (2012). International Journal of Biomedical and Advance Research, 3(9), 724-729. https://doi.org/10.7439/ijbar.v3i9.672
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