Analysis of observed values of glucose, creatinine, bilirubin and ALT examinations in Blood(Serum,Plasma) in hospital population

Authors

  • Heratkumar D. Soni 3rd year resident in Department of Biochemistry, Govt. Medical College, Surat, Gujarat (India)
  • Manisha P. Kapadia 3rd year resident in Department of Biochemistry , Govt. Medical College, Surat, Gujarat (India)
  • Kamal R. Modi 3rd year resident in Department of Biochemistry , Govt. Medical College, Surat, Gujarat (India)
  • Shaileshkumar M. Patel Professor and Head in Department of Biochemistry, Govt. Medical College, Surat, Gujarat (India)
  • Puneet Saxena Associate professor in Department of Biochemistry, Govt. Medical College, Surat , Gujarat (India)

DOI:

https://doi.org/10.7439/ijbar.v6i6.2130

Keywords:

WHO Modified partograph, Labour abnormalities, Maternal morbidity, Neonatal morbidity

Abstract

Objectives: Find reference range by Hoffman's method and compare it with published reference range in standard textbooks. Method: Observed values (results) of glucose (FBS, RBS and PP2BS), creatinine, bilirubin (total and direct) and ALT were collected from LIS of biochemistry section of New civil hospital surat laboratory services. Data were analysed using computarised hoffman's method as described by Alex K, Claudiu B and David WS2. Reference range derived by computarised hoffman's method were compared with published reference range in standard textbooks. Results and conclusion : The study shows that Hoffman method is useful for verification of reference range determined by direct methods when large numbers of data are available, distribution is more or less Gaussian and analyte in question is not etiologically responsible for a disease.

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References

Ashavaid TF, Todur SP, Dherai AJ. Establishment of reference intervals in Indian population Indian Journal of Clinical Biochemistry. 2005, 20 (2) 110-118.

Katayev A , Balciza C and Seccombe DW. Establishing Reference Intervals for Clinical Laboratory Test Results : Is There a Better Way?. Am J Clin Pathol 2010;133:180-186.

Burtis CA , Ashwood ER , Bruns DE. Tietz textbook of clinical chemistry and molecular diagnostics. Philadelphia Saunders an imprint of Elsevier Inc 2012.

NCCLS. How to Define and Determine Reference Intervals in the Clinical Laboratory; Approved Guideline

Bureau of Indian Standard(BIS), New Delhi . Medical laboratories

Bosma PJ, Chowdhury JR, Bakker C, Gantla S, de Boer A, Oostra BA, et al. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyl-transferase 1 in Gilbert's syndrome. N Engl J Med. 1995;333:1171

OWENS D. and EVANS J. . Population studies on Gilbert's syndrome . Journal of Medical Genetics (1975). 12, 152.

Longo DL, Fauci AS, Kasper DL, et al. Harrison's principles of internal medicine. McGraw-Hill Companies, Inc. 2012.

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Published

2015-06-30

Issue

Section

Original Research Articles

How to Cite

1.
Analysis of observed values of glucose, creatinine, bilirubin and ALT examinations in Blood(Serum,Plasma) in hospital population. Int J of Biomed & Adv Res [Internet]. 2015 Jun. 30 [cited 2024 Oct. 18];6(6):462-5. Available from: https://ssjournals.co.in/index.php/ijbar/article/view/2130

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