A prospective experimental comparative study on the clinical and antimicrobial effects of chlorine dioxide based toothpaste and mouthrinse in periodontitis patients- A One Year Follow-up Study

Abstract

Aim: The present study was aimed to assess and compare the clinical and antimicrobial effects of sodium chlorite based toothpaste and mouthrinse in periodontitis patients. Materials and methods: A total 50 generalized chronic periodontitis patient between the ages of 18 and 55 years were enrolled in the study and divided under two categories (A and B). Clinical and microbiological parameters were recorded prior to phase 1 therapy; and subjects were put on conventional oral hygiene regime and sodium chlorite based toothpaste and mouthrinse. Results: The results of this study showed that there was significant decrease in clinical, and microbiological parameters from baseline to 12 months in both the groups (p 0.01). The subjects under test group (sodium chlorite based toothpaste and mouthrinse) showed a highly significant reduction to all the parameters as compared to subjects under group B. Conclusion: sodium chlorite based toothpaste and mouthrinse will be a true alternative for maintaining oral hygiene.