Role of supplemental oxygen in reducing surgical site infection in acute appendicities: Our experience of sixty four cases

Abstract

Aim : To assess whether use of 80% oxygen reduces the frequency of surgical site infection in patients undergoing open appendectomy for appendicitis. Material and Methods : A randomised control study was conducted in the department of general surgery at NKP Salve Institute of Medical Sciences and Research Center and Lata Mangeshkar Hospital Nagpur. Sixty four patients undergoing open appendectomy via incision in the right lower quadrant of the abdomen were divided randomly into study group ie. patients receiving 80% oxygen during anesthesia, followed by high-flow oxygen for 2 hours in the recovery room and the control group receiving 30% oxygen, as usual. Surgical site infection will be assessed by the ASEPSIS (additional treatment, serous discharge, erythema, purulent discharge, separation of deep tissues, isolation of bacteria, and stay in hospital prolonged >14 days) system score. SPSS statistical software version 16.0 was used for data analysis. Results : The age distribution between the study and control group was statistically similar with p = 0.627. The sex distribution between the study and control group was statistically similar with p = 0.157. There were no medical comorbidities seen in both groups. The body temperature distribution between the study [mean SD = 37.020.12)] and control [mean SD = 37.06(0.24))] group was statistically similar with p = 0.272. Duration of abdominal pain was not significant with p=0.596. Preoperative analysis like WBC count, abdominal tenderness, Abdominal rigidity, hemoglobin, serum creatinine, blood urea, USG abdomen distribution was statistically not significant with p value >0.05. Duration of operation distribution between the groups was not significant with p=0.874. There was no surgical site infection seen in study as well as control group. All the cases in study as well as control group have satisfactory healing. There was significant (p=0.003) longer hospital stay in control group. Conclusion : Our study concludes that there is no role of supplemental oxygen in reducing surgical site infection in acute appendicitis.