SYNTHESIS AND ANTICONVULSANT SCREENING OF SOME NOVEL DERIVATIVES OF SUBSTITUTED BENZOFURAN

Authors

  • Mehnaz Kamal Integral University, Lucknow (U. P.)
  • Ashok K Shakya Faculty of Pharmacy and Medical Sciences, Amman University

DOI:

https://doi.org/10.7439/ijbar.v3i4.350

Keywords:

Spinal cord injury, neurological deficit, awareness, preventive safety measures

Abstract

A series of N -(2-benzoylbenzofuran-3-yl)-4-(substituted)butanamides (IIIa-f ) were synthesized in good yield and evaluated for anticonvulsant activity and neurotoxic study. The identity of the synthesized compounds was confirmed on the basis of their elemental analysis and spectral data. In anti-MES test compounds IIIb, IIIc, IIId and IIIf showed potent activity. Compounds IIIa and IIIe were less toxic as compared with the standard drug phenytoin.

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Author Biography

  • Mehnaz Kamal, Integral University, Lucknow (U. P.)
    Faculty of Pharmacy,

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Published

2012-05-01

Issue

Section

Original Research Articles

How to Cite

SYNTHESIS AND ANTICONVULSANT SCREENING OF SOME NOVEL DERIVATIVES OF SUBSTITUTED BENZOFURAN. (2012). International Journal of Biomedical and Advance Research, 3(4), 233-237. https://doi.org/10.7439/ijbar.v3i4.350