PHARMACEUTICAL OVERVIEW OF SPHERICAL CRYSTALLIZATION

Authors

  • Ritesh Suresh Bathe NRI Institute of Pharmacy, Bhopal
  • K Chourey NRI Institute of Pharmacy, Bhopal
  • D Khobragade NRI Institute of Pharmacy, Bhopal
  • R Charde

DOI:

https://doi.org/10.7439/ijbar.v3i1.245

Keywords:

Girardinia heterophylla, sitosterol, Ursolic acid

Abstract

Spherical crystallization is a particle design technique, by which crystallization and agglomeration can be carried out simultaneously in one step and which has been successfully utilized for improvement of flowability, compactability and bioavailability of crystalline drugs. General methods of spherical crystallization are spherical agglomeration, emulsion solvent diffusion and ammonia diffusion method. The principle steps involved in the process of spherical crystallization are flocculation zone, zero growth zone, fast growth zone and constant size zone. Spherical crystallization is having wide applications in pharmaceuticals like improvement of flowability and compressibility of poorly compressible drugs, masking bitter taste of drugs and improving the solubility and dissolution rate of poorly soluble drug.

Downloads

Download data is not yet available.

Author Biographies

  • Ritesh Suresh Bathe, NRI Institute of Pharmacy, Bhopal
    Assistant professor, Dept of Pharmaceutics
  • K Chourey, NRI Institute of Pharmacy, Bhopal
    Dept of Pharmaceutics
  • D Khobragade, NRI Institute of Pharmacy, Bhopal
    Professor, Dept of Pharmaceutics
  • R Charde
    Govt. College of Pharmacy, Amravati

Downloads

Published

2012-02-01

Issue

Vol. 3 No. 1 (2012): Jan

Section

Review Article

License

Authors who publish with this journal agree to the following terms:

  • Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  • Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  • Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (SeeThe Effect of Open Access).

How to Cite

PHARMACEUTICAL OVERVIEW OF SPHERICAL CRYSTALLIZATION. (2012). International Journal of Biomedical and Advance Research, 3(1), 01-06. https://doi.org/10.7439/ijbar.v3i1.245
Crossref
Scopus
Google Scholar
Europe PMC