Quantification of cinnarizine and dimenhydrinate in tablet dosage form by simultaneous equation spectrophotometric method
DOI:
https://doi.org/10.7439/ijapa.v4i2.68Keywords:
Formalin, Hazardous Effects, Medical Students, Bhopal.Abstract
Simple, accurate, precise, reproducible, requiring no prior separation and economical procedures for simultaneous estimation of Cinnarizine(CNZ) and Dimenhydrinate(DMH) in tablet dosage form have been developed. Method employs formation and solving of simultaneous equation using 250 nm and 277 nm as two analytical wavelengths for both drugs in methanol. CNZ and DMH at their respective ? max 250 nm and 277 nm shows linearity in a concentration range of 2-12 ?g /ml and 10-35 ?g /ml. Recovery studies for CNZ 98.9-100.75% and 96.16-100.69% for DMH in case of simultaneous equation method confirming the accuracy of the proposed method. The proposed method is recommended for routine analysis since it is rapid, simple, accurate and also sensitive and specific.Downloads
Downloads
Published
Issue
Section
License
Authors who publish with this journal agree to the following terms:
a) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
b)Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
c) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
After acceptance of the article, the author has to submit copyright form signed by all authors.
How to Cite
