Formulation and Characterization of Zingiberol Loaded Microsphere for Motion Sickness

Authors

  • Ayan Kumar Kar Department of Pharmaceutics, Calcutta Institute of Pharmaceutical Technology & AHS, Banitabla, Uluberia
  • Arijit Shil Department of Pharmaceutics, Calcutta Institute of Pharmaceutical Technology & AHS, Banitabla, Uluberia
  • Beduin Mahanty School of Pharmacy, Techno India University, Salt Lake, Kolkata, West Bengal

DOI:

https://doi.org/10.7439/ijap.v8i1.5258

Keywords:

Zingiberol, Microspheres, Ionotropic gelation method, Evaluation parameters

Abstract

The present research work involve the development of Zingiberol as the treatment of motion sickness. The Zingiberol microsphere was formulated by Ionotropic gelation method using different polymers in different ratio depending on RSM method. The prepared formulations were optimized on the basis of dependent variables like particle size (mg), entrapment efficiency etc. The SEM photographs of Zingiberol microsphere before dissolution shows the spherical and smooth surface whereas after dissolution the pores and crevices were shown which is indicating that the microsphere are showing drug release by diffusion mechanism. The microsphere formulations were able to sustain the release of drug both in vitro and in vivo. In the stability studies no significant change in drug entrapment release characteristics of the microspheres.

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Published

2019-11-30

Issue

Section

Research Articles

How to Cite

1.
Formulation and Characterization of Zingiberol Loaded Microsphere for Motion Sickness. Int J Adv Pharm [Internet]. 2019 Nov. 30 [cited 2024 Apr. 15];8(1):e5258. Available from: https://ssjournals.co.in/index.php/ijap/article/view/5258

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