EVALUATION OF ANTIDIABETIC POTENTIAL OF SELETED SPECIES OF SALACIA LEAF EXTRACT
DOI:
https://doi.org/10.7439/ijap.v5i5.3670Abstract
The objective of this study was to determine anti diabetic activity of selected seven species of Salacia such as Salacia beddomei, Salacia chinensis, Salacia fruticosa, Salacia gambleana, Salacia macrosperma, Salacia malabarica and Salacia oblonga .?-amylase and ?-glucosidase enzymes are two enzymes responsible for diabetic condition. The methanolic extract of seven species of Salacia was found to be effective against these two enzymes. The inhibitory activity of ?-amylase, S.beddomei shows IC 50 - 122g/ml , S.chinensis IC 50 - 112g/ml , S.fruticosa, IC 50 - 108g/ml , S.gambleana IC 50 - 148g/ml , S.macrosperma IC 50 - 125g/ml , S.malabarica IC 50 - 121g/ml , and S.oblonga IC 50 - 117g/ml. Inhibition of ?-glucosidase enzyme of seven species of Salacia such as S.beddomei, S.chinensis, S.fruticosa, S.gambleana, S.macrosperma, S.malabarica and S.oblonga showed IC 50 value of 107g/ml, 105g/ml, 80g/ml, 110g/ml, 109g/ml, 107g/ml and 108g/ml respectively, whereas standard Acarbose of ?-amylase and ?-glucosidase shows IC 50 value of 196 g/ml.Downloads
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Published
2016-10-30
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How to Cite
1.
EVALUATION OF ANTIDIABETIC POTENTIAL OF SELETED SPECIES OF SALACIA LEAF EXTRACT. Int J Adv Pharm [Internet]. 2016 Oct. 30 [cited 2026 Feb. 16];5(5):107-15. Available from: https://ssjournals.co.in/index.php/ijap/article/view/3670
