Formulation and Evaluation of microsphere of Rebiprazole Sodium

Authors

  • Ashwani Mishra Barkatullah University

DOI:

https://doi.org/10.7439/ijap.v5i3.3335

Abstract

Microspheres include microparticles and microcapsules (having a core of the drug) of 1-1000?m in diameter and consisting either entirely of a bioadhesive polymer or having an outer coating of it.In this work, an effort was made to formulate microsphere of Rabeprazole sodium by using different polymers. Prepared formulations are evaluated for bulk density, tapped density, percent mucoadhesion, Percent compressibility, Hausner's ration, percentage yield, size and surface morphology, interaction study by Differential scanning calorimeter and in vitro drug release. Formulation which passed all the evaluation parameters were considered as best formulation of Rabeprazole sodium.

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Author Biography

  • Ashwani Mishra, Barkatullah University
    Assistant Professor ,Department of Pharmacy

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Published

2016-07-02

Issue

Section

Research Articles

How to Cite

1.
Formulation and Evaluation of microsphere of Rebiprazole Sodium. Int J Adv Pharm [Internet]. 2016 Jul. 2 [cited 2026 Jan. 3];5(3):76-83. Available from: https://ssjournals.co.in/index.php/ijap/article/view/3335