UV-Visible Spectrophotometric Method Development and Validation of Itraconazole in Bulk and Capsule Formulation

Authors

  • Poonam A. Salunke Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jamner Tal- Jamner Dist- Jalgaon http://orcid.org/0000-0001-6154-6064
  • Kamlesh Ingale Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jamner, (M.S.)
  • Pooja Gondhankhede Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jamner, (M.S.)
  • Kanchan Ghate Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jamner, (M.S.)
  • Shital S. Patil Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jamner, (M.S.)
  • S. D. Barhate Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jamner, (M.S.)

DOI:

https://doi.org/10.7439/ijapa.v6i4.3833

Abstract

A simple, rapid, accurate and precise UV method was developed and validated for the estimation of Itraconazole in pharmaceutical dosage form. Spectroscopic method was carried out by using acidic ethanol as solvent. Itraconazole detection wavelength was set at 262nm for validation purpose linearity, accuracy, repeatability, precision, LOD, LOQ, and ruggedness parameters were studied. The linearity was found to be in the range of 2-12 g/ml.

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Author Biography

  • Poonam A. Salunke, Shree Sureshdada Jain Institute of Pharmaceutical Education and Research, Jamner Tal- Jamner Dist- Jalgaon
    Quality Assurance department

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Published

2016-12-30

Issue

Vol. 6 No. 4 (2016): Oct-Dec

Section

Research Articles

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How to Cite

1.
UV-Visible Spectrophotometric Method Development and Validation of Itraconazole in Bulk and Capsule Formulation. Int J of Adv in Phar Ana [Internet]. 2016 Dec. 30 [cited 2024 Oct. 18];6(4):21-6. Available from: https://ssjournals.co.in/index.php/ijapa/article/view/3833

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